For Data Monitoring Committee (DMC) reports, Biogen has moved from static, SAS-based reports to interactive R Markdown reports that allow users to immerse themselves in the data during review. While several stakeholders have welcomed this new way of working, this change has not been without challenges. This talk will go over the concept and execution of these reports, the strategies to overcome these challenges, and the benefits that switching to a web-based output has given to the organization.